Folding and Unfolding Mechanism of Designed Ankyrin Repea...
The 'protein folding problem', i.e. understanding the detailed steps of the protein folding pathways is one of the most challenging topics in biochemistry. Combining theoretical with experimental research became indispensable for the investigation of the mechanisms in protein folding reactions. Here, the biophysical characterization of designed ankyrin repeat (AR) proteins and the analysis of the experimental data by theoretical models ...