Nuclear-cytoplasmic translocation of the transporter regu...
The RS1 protein participates in regulation of Na+-D-glucose cotransporter SGLT1 and other solute carriers. In the present study, the mechanism and regulation of confluence-dependent nuclear location of RS1 was investigated. Nuclear location of RS1 was found to be regulated by the cell cycle. A nuclear shuttling signal (NS) in pRS1 was identified that mediates translocation of RS1 into and out ...